Visualizing the invisible while experiencing a fascination with science is the great challenge that Cell-to-Cell Communication, representing an all-new genre, has set out to meet. A spectacularly sophisticated computer animation in HD quality depicts the highly complex processes of intercellular interaction during an inflammatory periodontal reaction complete with the messenger molecules implicated. The various cell types constitute the main cast of the film, using a finely tuned communication process in their quest to destroy the bacterial invaders, with messenger molecules as supporting cast. The accompanying hardcover booklet includes the original film script and a quiz on the topics discussed in the film. A stunning didactic and dramatic experience!

Outline: Biofilm, Gingivitis and the Innate Immune Defense, Periodontitis and the Adaptive Immune Defense, Cleaning and Regeneration

Advisory Board: David L. Cochran, Jörg Meyle, Philip Preshaw, Mariano Sanz

Main Cast: Epithelial Cells, Macrophages, Granulocytes, Fibrolasts, Osteoblasts, Osteoclasts, Monocytes, T Cells, B Cells

Also Starring: Factor C3b, Factor C5b, Defensins, Factor C3a, Factor C5a, IL-1β, IL-6, TNF- α, Histamine, IL-8, RANK, M-CSF, Osteoprotegerin, RANKL, IL-17, MCP-1, RANTES, VEGF, FGF

Coming Soon: 
This film is the second module in a series of 3D animations that will make up the Education—Science Comes Alive 3D film library. Each film will explore a relevant biomedical process in dentistry and oral/maxillofacial surgery.